Yes, with a caveat which is latency. For example it's hard to split a typical webapp so the application servers are far from the database. The latency kills per

Yes, with a caveat which is latency. For example it's hard to split a typical webapp so the application servers are far from the database. The latency kills performance. On the other hand, for stuff like CI jobs, batch processing or anything else which doesn't depend on tight synchronization with the other location, you can mix and match.