3 ms·

I also noticed the article several days ago. Just wondering if there is any basic tutorial in python to analyze this type of data.

• fjfaase 7y ago
  I guess there is not much to analyze. Both the RNA sequence is given and their translation into amino-acids. The capital letters give the amino-acids. https://en.wikipedia.org/wiki/Amino_acid https://en.wikipedia.org/wiki/Amino_acid The lower case letter describe the RNA sequence. Sequences of three RNA base pairs are translated to one amino-acid. A table giving the standard decoding, can be found at: https://en.wikipedia.org/wiki/Genetic_code#RNA_codon_table https://en.wikipedia.org/wiki/Genetic_code#RNA_codon_table The next step is taking the amino-acids sequence and determine the protein structure. amino-acids chains fold together in a complex structure, which determine their function. Determining how this folding happens is a very complex problem. If you want to get some more idea about it, I suggest you have a look at https://fold.it/ https://fold.it/
  • zedr 7y ago
    Do you think research on 2019-nCoV would benefit from having available a platform for distributed computing, e.g. a dedicated Folding@Home?
    • fjfaase 7y ago
      I am afraid not. If there would be any, I guess it would already have been organized. No, knowing the structure of the proteins that make up the virus, might give some understand about how it works. If that gives some information about prevention (developping a vaccine) or treatment (developing anti-viral drugs), I wonder. Knowing the genetic code, can be helpful with developing vaccine. I understand that one approach is to incorporate part of the DNA in a known 'disabled' virus and test if it has some protective effect in some animals, and only after positive results test it on humans.