3 ms·
Yeah. Sure. That's possible. But how probable? >The intragastric LD50 with the emulsion was 800 mg/kg and with the sesame oil formulation, 1270 mg/kg. The iv L
by Red_Leaves_Flyy 7y ago
Yeah. Sure. That's possible. But how probable?
>The intragastric LD50 with the emulsion was 800 mg/kg and with the sesame oil formulation, 1270 mg/kg. The iv LD50 was 36–40 mg/kg, similar to the inhalation dose when the latter was corrected for Δ9-THC losses in the rodent nasal passages.
Taking a round 40mg/kg ld50, that's 1,818.181818..mg minimum for inhaled thc. That's about 6 grams of top shelf 30% thc marijuana. That's $30-180 retail. From all evidence I've seen someone is more likely, by at least an order of magnitude, to die by smoke inhalation, burning their house down, tripping down the stairs, or crashing their crash than successfully smoking themselves to death. I also find that ld50 suspicious and am curious to know their testing methodology. I don't have and reason to doubt the iv ld50, but I've also never heard of anyone anywhere ever slamming thc.
Taking the lower of the two ingested ld50s gets us to 121 grams, or a quarter pound of weed. That's around $200, on the cheap side. But if you were just to eat the buds I seriously doubt anything would happen at all. They're nutritious after all.
So, we need 36.3 grams of activated and concentrated thc, probably in the form of hash oil refill syringes. That's like $750 minimum. Realistically over $1500. It has a constituency thicker than molasses, and tastes pretty bad and you'll probably puke it up before it kills you unless you mix it down with something that's easier to palate, but then you're most likely increasing the ld50 to at least 58g.
Let's compare these values.
Pure nicotine: 300-600mg. A typical cigarette has 1mg or less nicotine. That's 15-30 packs. I'm assuming rather quick. Smoke inhalation would probably kill first. $75-150.
Alcohol 21oz 80 proof in an hour for a 120lb man. $5?
Opiates? Read some war stories. 10mg oxycontin could make some opiate niave people nod and puke. 80 could stop some peoples breathing. Yet some heavy users take 1,000mg+ plus 'safely'. (2)
Name brand opiate pills are expensive. If I'm remembering right its usually $1/mg.
Fentanyl? Carfentanyl? Pictures explain it better: https://dancesafe.org/wp-content/uploads/2017/07/fatal-doses.jpg https://dancesafe.org/wp-content/uploads/2017/07/fatal-doses...
$? a fraction of the name brands. Though you won't find hustling this in baggies or foil. It's possible to inhale enough airborne fentanyl to od. Hell, it could even just land on your skin and get absorbed.
As far as the possibility of fatal overdoses on recreational drugs goes, marijuana is basically benign.
1.https://www.sciencedirect.com/science/article/pii/0041008X74901264 https://www.sciencedirect.com/science/article/pii/0041008X74...
2. https://www.bluelight.org/xf/threads/how-much-over-your-normal-dose-is-od-territory-opiates.215723/ https://www.bluelight.org/xf/threads/how-much-over-your-norm...