5 ms·

shame, I did this a few weeks ago: http://github.com/orta/dna http://github.com/orta/dna

by orta 16y ago

timmorgan 16y ago
Manu said [1] he was the first to do so, but looks like maybe you beat him. [1] http://manu.sporny.org/2011/public-domain-genome/ http://manu.sporny.org/2011/public-domain-genome/
po 16y ago
I would say you dodged a bullet. This guy's repo is fast becoming a gag: https://github.com/msporny/dna/network/members https://github.com/msporny/dna/network/members Also, he explicitly released it under the Creative Commons Public Domain License. Incidentally, I wonder if that has any patent implications? Does having genomes in the public domain prevent pharma companies from patenting their "discoveries"?
- eru 16y ago
  The public domain shouldn't matter. Publication could.
- jarin 16y ago
  Aren't you not supposed to be able to patent facts? Seems like your DNA structure should be classified as a fact.
  - flipbrad 16y ago
    see the BRCA1/2 (myriad) debacle. horrible mess.
- ErrantX 16y ago
  Heh. The GitHubt default text on that page is accidentally funny in itself ;) msporny created dna and everyone else forked it. This is the family tree.
athom 16y ago
So, where/how do you get a dump of your DNA, anyways? I suppose it must cost a pretty penny, too?
- eru 16y ago
  He used 23andme. And they only give you data for around a million SNPs (http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism). The cost of sequencing decreases by a factor of 10 (!) a year per base pair. I will wait until it's cheap to sequence my whole genome, before I'll shell out the money. (Synthesizing also gets cheaper by around the same factor. But it started from a higher level of cost.)
  - wccrawford 16y ago
    I saw the XMas sales for 23andme and I thought the money at that time was well worth the knowledge. If and when they offer the service for a complete sequence, I'll probably pay the money again, just to have a complete record.
    - honm 16y ago
      Did you find anything interesting? Ailments or ancestry?
      - orta 16y ago
        I didn't, I found the 23andme website pretty boring, infact, it basically turned into a $200 git clone joke I made a few weeks ago
      - araneae 16y ago
        I found all of it interesting, but I'm a bio geek. I'm also planning to have kids with my fiancé so it's also cool because of that. Some highlights: Both my fiancé and I are carriers for a mild form of Hemochromatosis, so we have a 1/4 chance of having a kid with it. I am a little bit Asian! That's probably the Jewish ancestry. My fiancé thought he had a black ancestor but it turns out was 100% European. My best friend, whose father had always told her that her grandmother was Native American, found out he was lying to her (which did not surprise but did disappoint her.) Also the heat map of where your mitochondria are from is fun; it confirmed what I knew already but it was still really cool to see that the first migration of my maternal line out of Greece was with my grandmother. But that's really just the tip of the iceberg. Part of what makes 23andme so fun is you get to learn a lot about biology from the framework of your own genes. Each SNP they report on has a bunch of information associated with it. It's only boring if you aren't interested in biology.
Zpirate 16y ago
Well, it's not actually a genome, it's just 1 million snp locations. Genome is about 3.1 GB. For humans, at least.
mbreese 16y ago
In your README you state: I find it fascinating that you can get a text file, roughly 25meg big that contains what I'd imagine to be terabtyes worth of data I just thought I'd point out that you're really just getting a 25MB patch to a 3GB file (which is really duplicated to 6GB).
- orta 16y ago
  Ah, now that makes sense, thanks mbreese

shame, I did this a few weeks ago: http://github.com/orta/dna http://github.com/orta/dna

by orta 16y ago

shame, I did this a few weeks ago: http://github.com/orta/dna http://github.com/orta/dna

Manu said [1] he was the first to do so, but looks like maybe you beat him. [1] http://manu.sporny.org/2011/public-domain-genome/ http://manu.sporny.org/2011/public-domain-genome/

po 16y ago

I would say you dodged a bullet. This guy's repo is fast becoming a gag: https://github.com/msporny/dna/network/members https://github.com/msporny/dna/network/members Also, he explicitly released it under the Creative Commons Public Domain License. Incidentally, I wonder if that has any patent implications? Does having genomes in the public domain prevent pharma companies from patenting their "discoveries"?

eru 16y ago
The public domain shouldn't matter. Publication could.
jarin 16y ago
Aren't you not supposed to be able to patent facts? Seems like your DNA structure should be classified as a fact.
- flipbrad 16y ago
  see the BRCA1/2 (myriad) debacle. horrible mess.
ErrantX 16y ago
Heh. The GitHubt default text on that page is accidentally funny in itself ;) msporny created dna and everyone else forked it. This is the family tree.

athom 16y ago

So, where/how do you get a dump of your DNA, anyways? I suppose it must cost a pretty penny, too?

eru 16y ago
He used 23andme. And they only give you data for around a million SNPs (http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism). The cost of sequencing decreases by a factor of 10 (!) a year per base pair. I will wait until it's cheap to sequence my whole genome, before I'll shell out the money. (Synthesizing also gets cheaper by around the same factor. But it started from a higher level of cost.)
- wccrawford 16y ago
  I saw the XMas sales for 23andme and I thought the money at that time was well worth the knowledge. If and when they offer the service for a complete sequence, I'll probably pay the money again, just to have a complete record.
  - honm 16y ago
    Did you find anything interesting? Ailments or ancestry?
    - orta 16y ago
      I didn't, I found the 23andme website pretty boring, infact, it basically turned into a $200 git clone joke I made a few weeks ago
    - araneae 16y ago
      I found all of it interesting, but I'm a bio geek. I'm also planning to have kids with my fiancé so it's also cool because of that. Some highlights: Both my fiancé and I are carriers for a mild form of Hemochromatosis, so we have a 1/4 chance of having a kid with it. I am a little bit Asian! That's probably the Jewish ancestry. My fiancé thought he had a black ancestor but it turns out was 100% European. My best friend, whose father had always told her that her grandmother was Native American, found out he was lying to her (which did not surprise but did disappoint her.) Also the heat map of where your mitochondria are from is fun; it confirmed what I knew already but it was still really cool to see that the first migration of my maternal line out of Greece was with my grandmother. But that's really just the tip of the iceberg. Part of what makes 23andme so fun is you get to learn a lot about biology from the framework of your own genes. Each SNP they report on has a bunch of information associated with it. It's only boring if you aren't interested in biology.

Zpirate 16y ago

Well, it's not actually a genome, it's just 1 million snp locations. Genome is about 3.1 GB. For humans, at least.

mbreese 16y ago

In your README you state: I find it fascinating that you can get a text file, roughly 25meg big that contains what I'd imagine to be terabtyes worth of data I just thought I'd point out that you're really just getting a 25MB patch to a 3GB file (which is really duplicated to 6GB).

orta 16y ago
Ah, now that makes sense, thanks mbreese