9 ms·

can you ELI5 if this is bad? Should I not be taking Asprin or does that cause inflammation?

UnFleshedOne 7y ago
You should not be taking aspirin for headaches and such. It has worse side-effects than alternatives (thinning the blood, hard on stomach lining, children should not take it, can cause Reye's syndrome, etc).
gbear605 7y ago
Aspirin is an anti-inflammatory; it decreases inflammation. The hypothesis here is that the widespread use of it has caused decreased body temperatures through decreased levels of inflammation.
hwillis 7y ago
Nothing in this thread should affect your personal decisions, except the things about obesity and being sedentary. Don't do those things. Human body temperature varies naturally by about 5 degrees F. This study is talking about a .4 degree change. At the very least, your body can definitely handle it. This is purely an interesting phenomenon that may not even be real. Aspirin is very well-studied and definitely known to be very beneficial for your lifespan and quality of life. You should absolutely not throw away all that knowledge because it may be tangentially related to arbitrary theorizing (about inflammation) on a strange result on sketchy data from uncontrolled groups with unknowable biases. Medicine is proven to be good for you. Even if it does have unknown negative effects -even if this is an effect that we don't know about, that may not even be bad- you should not disregard medical wisdom for the sake of what you don't know.
ineedasername 7y ago
If you're talking about a daily dose, it is really something a doctor should be aware of and give a stamp of approval. It's a blood thinner, which means if you have any other anticoagulant med or issues it can be dangerous. Relatively speaking, it also has a fair low LD50. For a person around 150lb, 40 standard 325mg pills can be fatal. In fact you'll almost never, outside of hospital supply, find the 81mg chewable version in quantities higher than 36 in case children get a hold and think they're candy. Even then, a 2 year old downing a whole bottle would still be close to an LD50. All in all, despite being extremely common and cheap to the point of nearly free ($10 for a year's daily supply) it is actually less safe than other NSAID class drugs. But then none of this stuff, strictly speaking, is "safe" if it is used outside of it's normal use parameters.

You should not be taking aspirin for headaches and such. It has worse side-effects than alternatives (thinning the blood, hard on stomach lining, children should not take it, can cause Reye's syndrome, etc).

gbear605 7y ago

Aspirin is an anti-inflammatory; it decreases inflammation. The hypothesis here is that the widespread use of it has caused decreased body temperatures through decreased levels of inflammation.

hwillis 7y ago

Nothing in this thread should affect your personal decisions, except the things about obesity and being sedentary. Don't do those things. Human body temperature varies naturally by about 5 degrees F. This study is talking about a .4 degree change. At the very least, your body can definitely handle it. This is purely an interesting phenomenon that may not even be real. Aspirin is very well-studied and definitely known to be very beneficial for your lifespan and quality of life. You should absolutely not throw away all that knowledge because it may be tangentially related to arbitrary theorizing (about inflammation) on a strange result on sketchy data from uncontrolled groups with unknowable biases. Medicine is proven to be good for you. Even if it does have unknown negative effects -even if this is an effect that we don't know about, that may not even be bad- you should not disregard medical wisdom for the sake of what you don't know.

ineedasername 7y ago

If you're talking about a daily dose, it is really something a doctor should be aware of and give a stamp of approval. It's a blood thinner, which means if you have any other anticoagulant med or issues it can be dangerous. Relatively speaking, it also has a fair low LD50. For a person around 150lb, 40 standard 325mg pills can be fatal. In fact you'll almost never, outside of hospital supply, find the 81mg chewable version in quantities higher than 36 in case children get a hold and think they're candy. Even then, a 2 year old downing a whole bottle would still be close to an LD50. All in all, despite being extremely common and cheap to the point of nearly free ($10 for a year's daily supply) it is actually less safe than other NSAID class drugs. But then none of this stuff, strictly speaking, is "safe" if it is used outside of it's normal use parameters.