3 ms·
Perhaps this discovery could end up going the other way, with those newly discovered T-cells being the culprit in auto-immune diseases. Boosting their action wo
by alan-crowe 7y ago
Perhaps this discovery could end up going the other way, with those newly discovered T-cells being the culprit in auto-immune diseases. Boosting their action would be too dangerous to use as treatment for cancer, but knowing that they are there may lead to new treatments for auto-immune diseases.
And where does this fit into transplant rejection? Perhaps MR-1 differs enough between people to cause problems. This reads like the early days of a discovery that could lead anywhere.
- geerlingguy 7y agoAs someone with Crohn's and who knows people with all sorts of similar (maybe?) autoimmune diseases, any nugget of hope for something besides immunosuppressant treatment (meaning our bodies are always welcoming of other infections/sickness) is welcome.
- jonlucc 7y agoFortunately, the paper shows that this particular treatment doesn't attack normal cells, but it may cause trouble longer term (which is one reason additional safety studies are required before human trials). Also, I'm pretty sure there is already an increase in autoimmune disorders after current immuno-oncology (IO) treatment. Patients should certainly have that information before treatment.