A popular vote "disenfranchises" any voting bloc that stands in opposition to a majority. Do you believe this strategy of ameliorating tyranny-of-the-majority s

A popular vote "disenfranchises" any voting bloc that stands in opposition to a majority. Do you believe this strategy of ameliorating tyranny-of-the-majority scenarios by weighting votes generalizes to demographics other than place of residence? Can we give extra votes to all disadvantaged populations, or is there something unique about small-state folks?