Not probable and highly likely to be confounded by secular and social cofactors. These dietary models and recommendations in humans are dumb “one size fits all”

Not probable and highly likely to be confounded by secular and social cofactors. These dietary models and recommendations in humans are dumb “one size fits all”. We know from extensive animal research that genome-by-environmental effects are pervasive and can be large. For example in a highly diverse family of mice, a very high fat diet—60% calories from lard—is advantageous in terms of longevity in a few family members; although also true that this extreme diet is generally deleterious (see bioRxiv paper by Suheeta Roy and colleagues, GXE BXD study, 2019). The contrast between whole milk and no-fat milk is a comparatively subtle dietary shift. Extraordinary claims require extraordinary evidence, especially when they can impact millions of humans.