Especially since then you can't compare to prior trial data to newer trial data to see how they were crafting the selection process, which could derive hints fo

Especially since then you can't compare to prior trial data to newer trial data to see how they were crafting the selection process, which could derive hints for contraindications and the like - or simply to know if some medication is poorly distributed, in the sense of making sure a person fits the exact criteria, then its side-effects and damages will be far greater than what was approved at the end.