In my experience, most pure python code will be 10 to 100x faster if it’s rewritten in C++. So I just profile it as usual using cProfile, try to make algorithmi

In my experience, most pure python code will be 10 to 100x faster if it’s rewritten in C++. So I just profile it as usual using cProfile, try to make algorithmic improvements (eg caching) and then, if I need another order of magnitude, rewrite it in C++. So basically anything where the hot path is in pure Python, rather than a standard library method.