Not only that, but these articles always say the "what" and not the "why". Daily consumption of alcohol for example, depletes glutathione. The more you drink,

Not only that, but these articles always say the "what" and not the "why". Daily consumption of alcohol for example, depletes glutathione. The more you drink, the more that is depleted. Once your reserves are gone, the liver will still protect you, at the cost of itself. It essentially slowly self destructs to neutralize the alcohol once the glutathione is gone. People will always give examples of someone they knew that lived to 100 and had a shot of whiskey every day. Makes sense, they were replenishing their glutathione reserves faster than depleting it. It's obviously much more complicated of a process than what I described, but people don't have a way to measure it. The liver will try to detox people until it hits something like 5% capacity and then the symptoms are really obvious. By then, it is too late.