4 ms·Have you noticed a noticeable difference between Trikafta and the drug(s) that you were taking prior to this?by jdhn 7y agoHave you noticed a noticeable difference between Trikafta and the drug(s) that you were taking prior to this?bdcravens 7y agoI took the precursor to Trikafta, Orkambi. It’s not a huge difference but I definitely feel better now.jdhn 7y agoVery cool, glad to hear it's working out for you!