3 ms·

1 gram of NMN, metformin and resveratrol. Beyond that I take other things including carbon 60. Those are the most exotic items; the rest are your usual items su

by evo_9 7y ago

1 gram of NMN, metformin and resveratrol. Beyond that I take other things including carbon 60. Those are the most exotic items; the rest are your usual items such as fish-oil, krill oil, multi-vitiman most of which I tuned from my Inside-Tracker.com blood results. I also have the right genetics; aka longevity gene(s), Ashkenazi Jew markers, etc and my farther is in his upper 80's; his mother lived to 98. I don't want to claim that it's any one thing. I'm sure it's everything. The Tabata style sprinting 2-3 days a week, the hour+ workouts minimum of 5 days a week, the 16/8 fasting, the hockey/cryotherapy-like effects of being cold and working out/aerobic exhaustion of being on the ice or skating outside etc. And of course diet... I eat much much less than most people I know (big fan of Paleo menu by Green-Chef). The way I see it is there are studies around NMN, metformin and resveratrol right now; let's say in 10 years they all prove they slow aging/extend life... to me it's worth the cost to take these now and bet on a positive outcome. If some of these studies don't pan out, so it goes, but so far it seems like it's working out pretty well if my increasingly annoyed friends are any indication.

lossolo 7y ago
Does your father looks a lot younger too? My father is in his mid 50s and he looks 40. I am in my mid 30s and I look younger too. This is genetics obviously. I am also doing fasting 16/8 and eat less than most people. It's possible that those supplements have 0 effects and it's all just genetics.
- evo_9 7y ago
  Not really but he smoked for 40 years before quitting around age 55. Or it’s possible the preliminary results are correct.
  - lossolo 7y ago
    > Not really but he smoked for 40 years before quitting around age 55. My father smoked for around 30 years, I've smoked for around 16 years. > Or it’s possible the preliminary results are correct. Sure, it's a possibility too, I would like to see more long term studies tough, with enough participants to statistically exclude all environmental noise. For now we can be sure of one thing, genetics is the main factor in how we age.
LinuxBender 7y ago
I do all of those things, but I am finding the NMN to be quite costly. I take almost the same amount as Dr. Sinclair, which means going through a bottle of pills every three to five days. I really hope someone makes a less expensive version soon. I do feel the difference and can probably attribute it to higher ATP production. I have no idea if it's helping my cardio vascular system.
- evo_9 7y ago
  You'll notice if you stop; that's what happened to me when my NMN went on back-order and stopped for 8 days. Like metformin NMN doesn't produce any significant immediate noticeable effect like Alpha-GPC for example; it's more like working out - overtime the long-term effects are significant. At least that's the hope. I buy my NMN in a month supply at a time (150 a month).
- lachlan-sneff 7y ago
  How many milligrams of NMN do you take each day?
  - LinuxBender 7y ago
    Approx 800mg. The pill size varies with vendor so sometimes a little more and sometimes a little less.
    - lachlan-sneff 7y ago
      How are you getting that much without bankrupting yourself? It's extremely expensive, even in bulk powder form.
      - LinuxBender 7y ago
        I second that. I have to spend a lot to get 800mg/day. That's why I would love to see more companies make it and the price come down. I fully understand the molecule is a little more complex than its precursor, but maybe if more people made it, then the price would come down? /shrug
Varriount 7y ago
Don't you need a prescription for those supplements (or at least, metformin)?
- extesy 7y ago
  You can substitute it with over-the-counter Berberine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/
  - evo_9 7y ago
    Or take both like I do. Berberine is not as effective as metformin, but every bit helps when lowering blood sugar levels go.
    - extesy 7y ago
      Where do you get metformin from?
UncleOxidant 7y ago
I've seen some articles suggesting that berberine (plus sylamarin) may be superior to metformin with fewer side effects (plus it's cheaper and doesn't require a prescription).

by evo_9 7y ago

lossolo 7y ago

Does your father looks a lot younger too? My father is in his mid 50s and he looks 40. I am in my mid 30s and I look younger too. This is genetics obviously. I am also doing fasting 16/8 and eat less than most people. It's possible that those supplements have 0 effects and it's all just genetics.

evo_9 7y ago
Not really but he smoked for 40 years before quitting around age 55. Or it’s possible the preliminary results are correct.
- lossolo 7y ago
  > Not really but he smoked for 40 years before quitting around age 55. My father smoked for around 30 years, I've smoked for around 16 years. > Or it’s possible the preliminary results are correct. Sure, it's a possibility too, I would like to see more long term studies tough, with enough participants to statistically exclude all environmental noise. For now we can be sure of one thing, genetics is the main factor in how we age.

LinuxBender 7y ago

I do all of those things, but I am finding the NMN to be quite costly. I take almost the same amount as Dr. Sinclair, which means going through a bottle of pills every three to five days. I really hope someone makes a less expensive version soon. I do feel the difference and can probably attribute it to higher ATP production. I have no idea if it's helping my cardio vascular system.

evo_9 7y ago
You'll notice if you stop; that's what happened to me when my NMN went on back-order and stopped for 8 days. Like metformin NMN doesn't produce any significant immediate noticeable effect like Alpha-GPC for example; it's more like working out - overtime the long-term effects are significant. At least that's the hope. I buy my NMN in a month supply at a time (150 a month).
lachlan-sneff 7y ago
How many milligrams of NMN do you take each day?
- LinuxBender 7y ago
  Approx 800mg. The pill size varies with vendor so sometimes a little more and sometimes a little less.
  - lachlan-sneff 7y ago
    How are you getting that much without bankrupting yourself? It's extremely expensive, even in bulk powder form.
    - LinuxBender 7y ago
      I second that. I have to spend a lot to get 800mg/day. That's why I would love to see more companies make it and the price come down. I fully understand the molecule is a little more complex than its precursor, but maybe if more people made it, then the price would come down? /shrug

Varriount 7y ago

Don't you need a prescription for those supplements (or at least, metformin)?

extesy 7y ago
You can substitute it with over-the-counter Berberine: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839379/
- evo_9 7y ago
  Or take both like I do. Berberine is not as effective as metformin, but every bit helps when lowering blood sugar levels go.
  - extesy 7y ago
    Where do you get metformin from?

UncleOxidant 7y ago

I've seen some articles suggesting that berberine (plus sylamarin) may be superior to metformin with fewer side effects (plus it's cheaper and doesn't require a prescription).