I'd definitely start with the Eric Meyer reset before writing custom css just to get rid of any defaults you might be unaware of... http://meyerweb.com/eric/to

I'd definitely start with the Eric Meyer reset before writing custom css just to get rid of any defaults you might be unaware of... http://meyerweb.com/eric/tools/css/reset/ http://meyerweb.com/eric/tools/css/reset/ I'm also a fan of the 960.gs grid, really quick to learn and good for the majority of structured layouts.