looking at the first step in that graphic, for example, a histone is made of 4 distinct types of parts, and in humans each of those has a dozen variants, and th

looking at the first step in that graphic, for example, a histone is made of 4 distinct types of parts, and in humans each of those has a dozen variants, and the final assembled histone can additionally be tagged with other pieces. and the physical interaction between the histone and the DNA is influenced by the local sequence. I don't know how I would quantify that, but there's a lot going on.