3 ms·
Not true. Evidence is building that tau protein import to neurons activates the inflammasome, which causes cell death and local inflammation, if I skimmed this
by mjfl 7y ago
Not true. Evidence is building that tau protein import to neurons activates the inflammasome, which causes cell death and local inflammation, if I skimmed this paper right:
https://www.nature.com/articles/s41586-019-1769-z https://www.nature.com/articles/s41586-019-1769-z
the cell death would presumably lead to the accumulation of more tau, a destructive feedback loop.