'I would argue that failure to reproduce is perhaps the worst kind of scientific failure, because the activity cannot be called science anymore.' This is only

'I would argue that failure to reproduce is perhaps the worst kind of scientific failure, because the activity cannot be called science anymore.' This is only true if the results of research are deterministic. In many fields, if a study is estimating an effect that exists in the world as a distribution, a failure to reproduce might not be indicative of...anything.