3 ms·
Follow-up question that comes to mind: what happens to the fats and sugars when they don't get "accumulated"? Do they hang around in the blood, temporarily rais
by firethief 7y ago
Follow-up question that comes to mind: what happens to the fats and sugars when they don't get "accumulated"? Do they hang around in the blood, temporarily raising blood sugar and triglycerides? If so, how bad is that, if you do it frequently?
IIUC, obesity is bad partly because it's a sign of excess caloric nutrients in the body and therefore chronically high blood sugar and triglycerides (and partly for other reasons, like inflammatory signalling by fat tissues). I don't know the relative significance of these different factors, but I have to wonder if this effect of caffeine is hiding one obvious sign of problems while exacerbating the problems themselves.
ETA: it looks like they found that caffeine also had blood-triglyceride-reducing effects, partly by reducing lipogenesis. I would think this would shift all of the burden to blood sugar. I don't see anything about blood sugar levels.
ETA: I did some further research. Caffeine does acutely raise blood sugar levels[1], but caffeine intake is inversely-correlated with T2D[2]. The reason doesn't seem to be known yet, and I don't know if anyone's ruled out the obvious confounder that people who drink more coffee drink less Coke.
1: https://www.sciencedirect.com/science/article/pii/S0140673667915930 https://www.sciencedirect.com/science/article/pii/S014067366...
2: https://www.ncbi.nlm.nih.gov/pubmed/15998896 https://www.ncbi.nlm.nih.gov/pubmed/15998896
- dnautics 7y agore ETA2: if it acutely raises blood sugar levels by pulling it out of storage cells, then it makes sense that the baseline chronic sugar levels would be lower, by mass balance; and the development of T2D is more dependent on chronic blood sugar levels, not acute swings. Not saying this is the mechanism, it is just that the correlation should not be suprising.