3 ms·
https://www.caymanchem.com/msdss/14041m.pdf https://www.caymanchem.com/msdss/14041m.pdf Acute toxicity level 4 for Oral ingestion https://www.ilo.org/legacy/e
by JackRabbitSlim 7y ago
https://www.caymanchem.com/msdss/14041m.pdf https://www.caymanchem.com/msdss/14041m.pdf
Acute toxicity level 4 for Oral ingestion
https://www.ilo.org/legacy/english/protection/safework/ghs/ghsfinal/ghsc05.pdf https://www.ilo.org/legacy/english/protection/safework/ghs/g...
Defines Toxicity level 4 as ~ 2000 to < 5000 mg/kg
The most potent strain of "magic mushrooms" are at most ~2% by weight(Psilocybe azurescens)[0]. So according to all the de facto standard literature, a potentially fatal dose of magic mushrooms is over 3 ounces of dried mushroom per kilogram of body weight. At 68 kg I would need to ingest over 5 kg to come up to the lower bound of the LD50.
No one without an axe to grind could realistically argue toxicity is a real valid concern.
[0]https://www.shroomery.org/8700/Psilocybe-azurescens-taxonomy-paper https://www.shroomery.org/8700/Psilocybe-azurescens-taxonomy...
- arkades 7y agoAcute toxicity and LD50/fatal dosages are fine when you're worried about acute overdoses or unintentional ingestions. Those are not the measures we are concerned with when we're talking about uncommon or rare effects (which, like the Vioxx deaths, had an incidence of one in /thousands/ at standard dosages), or effects that manifest with /chronic/ usage (e.g., over years of use, as is common with anti-depressant therapy). What you're discussing is apples to oranges.
- internet_user 7y agoIt's not about toxicity, but tolerability limits and side-effect profile.