5 ms·

Would going back to the trivalent solve all of the problems?

• tempestn 7y ago
  It should reduce the number of flare-ups of type 2, since everyone would be protected again, but you'd also be back to the situation where anyone could be exposed due a vaccine derived case. The goal is to eradicate the disease completely so that the vaccine doesn't need to be used, since it can trigger cases. Going back to the trivalent (ie going back to distributing the type 2 vaccine widely) would be a step back from that goal, albeit maybe a necessary one.
• marcinzm 7y ago
  According to the article, the trivalent vaccine is a live virus and occasionally reverts to a virulent strain. So while the trivalent vaccine can generally stop outbreaks it also paradoxically causes them in a tiny percentage of cases. Using it means you cannot eradicate the virus entirely as the vaccine itself causes new outbreaks.
  • trianglem 7y ago
    I wonder if there is any sort of genetic basis to who might get sick from the trivalent in the small percentage of cases. Not that it’s a viable strategy but then you could selectively give those people only the trivalent.