> True, but placebo effect is random and uncorrelated with the change. No, it's not. The definition of placebo effect is that a placebo works differently from

> True, but placebo effect is random and uncorrelated with the change. No, it's not. The definition of placebo effect is that a placebo works differently from not placebo. > Otherwise big pharma would just replace all drugs with sugar pills. No, because in many cases drugs work better than placebo.