In the context of web-based startups, you can assume 99% of the time content will dictate the design, and that the site will grow in content rather quickly. Tha

In the context of web-based startups, you can assume 99% of the time content will dictate the design, and that the site will grow in content rather quickly. That said, the grid is one of the most modular structures for plugging in content without disrupting or rebuilding the entire flow. Why re-invent the wheel? The grid concept is universal, and certainly helps during planning for prioritizing real estate and architecting your information properly.