An equivalent to Spring Test + JUnit in Python might be Django's testing framework, which extends the standard library's unittest module. REST Assured might not

An equivalent to Spring Test + JUnit in Python might be Django's testing framework, which extends the standard library's unittest module. REST Assured might not need an equivalent - the documentation says it "brings the simplicity of using [dynamic languages such as Ruby and Groovy] into the Java domain". As for Hamcrest, I don't know what you would use with unittest (other than the build-in assertions), but I think pytest does some clever introspection to give similar results when it comes to error reporting. Since I've only tried the boring default options, I'd be interested to learn about the more esoteric ones people are using. Could you give examples of some of the permutations of Python test libraries you have run into in practice?