3 ms·

LSD is used in ridiculously minute quantities, with standard doses measured in micrograms (millionths of a gram). It's astonishing enough that this can have a

LSD is used in ridiculously minute quantities, with standard doses measured in micrograms (millionths of a gram). It's astonishing enough that this can have a profound effect on the brain, but it's highly unlikely to cause physical damage to larger organs like the heart.

colordrops 7y ago
The size of the dose is not a great measure of safety. Botulinum toxin has an LD50 in the nanograms, and several other toxins in the same range of LSD, that being micrograms. Now no strong evidence of toxicity has been found from LSD, but that's not due to it being taken in small doses.
papreclip 7y ago
In theory, every LSD dose consumed is pure LSD. In practice there are many stand-ins that are cheaper and easier to produce. They have different tox profiles and one never knows what one is actually taking unless you run your samples through a battery of quantitative tests. The one or two field tests out there are easily fooled if the counterfeiter is of a mind to fool them
- tim333 7y ago
  I'm not sure that's true for LSD. It's much stronger per mg than other such drugs and as a result tends to be added to other things rather than having things added to it.
  - papreclip 7y ago
    My understanding is that synthesizing even one atom of LSD is probably more expensive and difficult than making several grams of some NBOMe derivative. The production costs don't scale to zero and the synthesis itself is beyond the abilities of some "drug cooks" Don't have any personal experience. I was a grad student working on organic synthesis once but never did anything illegal
- stjohnswarts 7y ago
  Too bad it's not legal and regulated. I personally am just fine with reality and don't use any reality altering drugs but it would a lot safer if LSD was a regulated substance that the FDA could insure its quantity and quality.

3 ms·

LSD is used in ridiculously minute quantities, with standard doses measured in micrograms (millionths of a gram). It's astonishing enough that this can have a

by 9nGQluzmnq3M 7y ago

colordrops 7y ago
The size of the dose is not a great measure of safety. Botulinum toxin has an LD50 in the nanograms, and several other toxins in the same range of LSD, that being micrograms. Now no strong evidence of toxicity has been found from LSD, but that's not due to it being taken in small doses.
papreclip 7y ago
In theory, every LSD dose consumed is pure LSD. In practice there are many stand-ins that are cheaper and easier to produce. They have different tox profiles and one never knows what one is actually taking unless you run your samples through a battery of quantitative tests. The one or two field tests out there are easily fooled if the counterfeiter is of a mind to fool them
- tim333 7y ago
  I'm not sure that's true for LSD. It's much stronger per mg than other such drugs and as a result tends to be added to other things rather than having things added to it.
  - papreclip 7y ago
    My understanding is that synthesizing even one atom of LSD is probably more expensive and difficult than making several grams of some NBOMe derivative. The production costs don't scale to zero and the synthesis itself is beyond the abilities of some "drug cooks" Don't have any personal experience. I was a grad student working on organic synthesis once but never did anything illegal
- stjohnswarts 7y ago
  Too bad it's not legal and regulated. I personally am just fine with reality and don't use any reality altering drugs but it would a lot safer if LSD was a regulated substance that the FDA could insure its quantity and quality.