4 ms·

>First, it just shows that it is safe. It is expected, LSD is one of the safest drugs out there. Yes, certainly. A drug that can trigger a psychosis after taki

>First, it just shows that it is safe. It is expected, LSD is one of the safest drugs out there. Yes, certainly. A drug that can trigger a psychosis after taking it only a single time and that can give its users persistent hallucinations[1] is one of the safest drugs out there. The drug propaganda gets completely out of control. Edit: Not to forget that taking LSD can permanently change your personality.[2] In most cases these changes may appear positive, but there is probably a potential for permanent negative changes. [1]: https://slatestarcodex.com/2019/09/11/lots-of-people-going-around-with-mild-hallucinations-all-the-time/ https://slatestarcodex.com/2019/09/11/lots-of-people-going-a... [2]: https://link.springer.com/article/10.1007/s00213-017-4733-3 https://link.springer.com/article/10.1007/s00213-017-4733-3

cmrdporcupine 7y ago
Yep over the years I have met many people with the story about the person with latent schizophrenia who switches from functional to extremely ill after a single LSD trip. I knew someone like this in my youth, and have since heard about many other cases. One of the more famous examples is the musician Daniel Johnston. LSD is powerful and not to be messed around with lightly. Yes, it's not heroin or meth. But it's a powerful chemical whose effects can vary wildly from person to person and setting to setting.
GuB-42 7y ago
And I totally agree... But I meant it in a "not a poison" sense, meaning it won't kill you. That's why I explicitly mentioned "LSD poisoning". I should have been more clear. I have heard of HPPD and looked it up, but found nothing conclusive. I don't deny that it is real but we really don't know much about it. One problem is that we know that it happens to LSD users, but that's usually not the only drug they use, and due to its illegal nature, we are not even sure that's really LSD. There are LSD substitutes like NBOMe that have similar effects but are much more unsafe. To my knowledge, none of it happened in controlled studies. I agree with the changes in personality that can be negative. But an important part is that the study is about microdoses. Doses that are not enough to give you hallucinations. My personal theory is that the life-changing effects of LSD come from experiencing the hallucinations. These can be really intense, they are nothing like you ever felt before, and unlike dreams, they are memorable. And like any intense experience, they are bound to affect your life, for the better or for the worse. In fact, "flashbacks" have a lot in common with PTSD, so much that I think they really are PTSD, with the (usually bad) trip being the traumatic event. But microdoses don't create these kinds of intense experiences. So combined with the fact it is essentially non-toxic for your body, I am not at all surprised that it passed all the safety tests. The really interesting part will be about effectiveness.
1000units 7y ago
MKUltra and similar programs brought LSD into certain academic/nerd circles many years ago and broke their brains. This is why you are being downvoted (ironically enough).
xorfish 7y ago
Any studies that show an increased risk for psychosis after a single dose?

cmrdporcupine 7y ago

Yep over the years I have met many people with the story about the person with latent schizophrenia who switches from functional to extremely ill after a single LSD trip. I knew someone like this in my youth, and have since heard about many other cases. One of the more famous examples is the musician Daniel Johnston. LSD is powerful and not to be messed around with lightly. Yes, it's not heroin or meth. But it's a powerful chemical whose effects can vary wildly from person to person and setting to setting.

GuB-42 7y ago

And I totally agree... But I meant it in a "not a poison" sense, meaning it won't kill you. That's why I explicitly mentioned "LSD poisoning". I should have been more clear. I have heard of HPPD and looked it up, but found nothing conclusive. I don't deny that it is real but we really don't know much about it. One problem is that we know that it happens to LSD users, but that's usually not the only drug they use, and due to its illegal nature, we are not even sure that's really LSD. There are LSD substitutes like NBOMe that have similar effects but are much more unsafe. To my knowledge, none of it happened in controlled studies. I agree with the changes in personality that can be negative. But an important part is that the study is about microdoses. Doses that are not enough to give you hallucinations. My personal theory is that the life-changing effects of LSD come from experiencing the hallucinations. These can be really intense, they are nothing like you ever felt before, and unlike dreams, they are memorable. And like any intense experience, they are bound to affect your life, for the better or for the worse. In fact, "flashbacks" have a lot in common with PTSD, so much that I think they really are PTSD, with the (usually bad) trip being the traumatic event. But microdoses don't create these kinds of intense experiences. So combined with the fact it is essentially non-toxic for your body, I am not at all surprised that it passed all the safety tests. The really interesting part will be about effectiveness.

1000units 7y ago

MKUltra and similar programs brought LSD into certain academic/nerd circles many years ago and broke their brains. This is why you are being downvoted (ironically enough).

xorfish 7y ago

Any studies that show an increased risk for psychosis after a single dose?