3 ms·

Do you have evidence beyond indirect second hand anecdotes that might support your hypothesis?

nabla9 7y ago
I think op is only partially right. There seems to be indirect connection trough insulin and insulin like growth factors. They can play important role in oncogenesis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/
aiphex 7y ago
This is not new information. And it's been shown to be efficacious. The problem is patient adherence. Chemo is something that so long as the patient shows up you can administer it and they can go back home. A glucose free diet could only be adhered to on an in-patient basis. Which most patient / healthcare systems cannot afford. There have also been studies showing efficacy of a compound which down regulates Glut1 in order to cut off glycolysis in cancer cells which rely solely on it for energy production.
- whatshisface 7y ago
  >A glucose free diet could only be adhered to on an in-patient basis. That's not true, the Keto diet is a big fad and it only works if your diet is basically glucose free.
  - JoeAltmaier 7y ago
    Dieting is notoriously difficult to follow 100%. And in this case that's important. In-patient, the intake is exactly what the dietician (and indirectly the doctor) prescribes. A better outcome could be expected.
  - firethief 7y ago
    I have doubts about a couple of the assumptions implicit in this statement. - The "Keto" diet particularly works. Last time I checked, the research suggested it worked about as well as any other elimination diet, or vanilla CR. - The reason it works. Given that it works about as well as any other elimination diet, it's probably important for practitioners to adhere strictly, rather than continuing to consume the foods that made them fat; but successfully avoiding carbohydrate intake enough to trigger some particular level of ketosis is probably not a part of how it "works".
    - whatshisface 7y ago
      Neither of those assumptions were implicit in the statement. The keto diet is simply evidence that glucose elimination is possible for some people without an inpatient treatment. The context of this discussion is glucose elimination for cancer, not weight loss.
      - firethief 7y ago
        (There is a fad that people attempt to do X) + (the observable result is orthogonal to whether they successfully did X) => not very strong evidence that doing X is achievable

I think op is only partially right. There seems to be indirect connection trough insulin and insulin like growth factors. They can play important role in oncogenesis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/

aiphex 7y ago

This is not new information. And it's been shown to be efficacious. The problem is patient adherence. Chemo is something that so long as the patient shows up you can administer it and they can go back home. A glucose free diet could only be adhered to on an in-patient basis. Which most patient / healthcare systems cannot afford. There have also been studies showing efficacy of a compound which down regulates Glut1 in order to cut off glycolysis in cancer cells which rely solely on it for energy production.

whatshisface 7y ago
>A glucose free diet could only be adhered to on an in-patient basis. That's not true, the Keto diet is a big fad and it only works if your diet is basically glucose free.
- JoeAltmaier 7y ago
  Dieting is notoriously difficult to follow 100%. And in this case that's important. In-patient, the intake is exactly what the dietician (and indirectly the doctor) prescribes. A better outcome could be expected.
- firethief 7y ago
  I have doubts about a couple of the assumptions implicit in this statement. - The "Keto" diet particularly works. Last time I checked, the research suggested it worked about as well as any other elimination diet, or vanilla CR. - The reason it works. Given that it works about as well as any other elimination diet, it's probably important for practitioners to adhere strictly, rather than continuing to consume the foods that made them fat; but successfully avoiding carbohydrate intake enough to trigger some particular level of ketosis is probably not a part of how it "works".
  - whatshisface 7y ago
    Neither of those assumptions were implicit in the statement. The keto diet is simply evidence that glucose elimination is possible for some people without an inpatient treatment. The context of this discussion is glucose elimination for cancer, not weight loss.
    - firethief 7y ago
      (There is a fad that people attempt to do X) + (the observable result is orthogonal to whether they successfully did X) => not very strong evidence that doing X is achievable