Yes, we picked the low hanging fruit a long time ago - the rare variants causing devlopmental defects etc. This is not what we are talking about. As for your p

Yes, we picked the low hanging fruit a long time ago - the rare variants causing devlopmental defects etc. This is not what we are talking about. As for your predictions - they've been said over and over again ever since I started embarking on the genomics hype 7 years ago. The reality is much more boring and selecting for complex traits that heavily interact with the environment is bound to have disappointing returns.