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> The advent of second-generation sequencing technologies allows for the retrieval of ancient genomes from long-dead people and, using non-human sequencing read
by kbenson 7y ago
> The advent of second-generation sequencing technologies allows for the retrieval of ancient genomes from long-dead people and, using non-human sequencing reads, of the pathogens that infected them.
This is pretty cool. I'm not sure what state of the art is in DNA sequencing, but it sounds like this is impressive. The abstract mentions that it's the oldest DNA sequencing sourced the celluloid (a newspaper in this case), but I don't know if there are successes from other sources that are older.
- est31 7y agoQuick googling tells me the current record is a horse from hundreds of thousands of years ago: https://www.nature.com/articles/nature12323 https://www.nature.com/articles/nature12323 I wonder though whether it's been replicated and whether there were any differences in the outcome.
- mnemonicsloth 7y agoSecond generation sequencing is fast and in wide use. Third generation sequencing is the new hotness https://en.wikipedia.org/wiki/Third-generation_sequencing https://en.wikipedia.org/wiki/Third-generation_sequencing