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Kratom is not an opioid. https://www.health.harvard.edu/blog/kratom-fear-worthy-foliage-or-beneficial-botanical-2019080717466 https://www.health.harvard.edu/bl
by taxidump 7y ago
Kratom is not an opioid.
https://www.health.harvard.edu/blog/kratom-fear-worthy-foliage-or-beneficial-botanical-2019080717466 https://www.health.harvard.edu/blog/kratom-fear-worthy-folia...
- loeg 7y agoHow isn't it? > Opioids are substances that act on opioid receptors[1] From your link[2]: > The two main chemicals, mitragynine and 7-hydroxymitragynine, have strong activity at the main opioid receptor, the “mu” receptor, which is the same one stimulated by heroin and oxycodone. It's not an opiate, which is just the subset of opioids derived from the opium poppy. But neither are many pharmaceutical opioids. [1]: https://en.wikipedia.org/wiki/Opioid https://en.wikipedia.org/wiki/Opioid [2]: https://www.health.harvard.edu/blog/kratom-fear-worthy-foliage-or-beneficial-botanical-2019080717466 https://www.health.harvard.edu/blog/kratom-fear-worthy-folia...
- GordonS 7y agoIt binds to opioid receptors - it is an opioid. I realise it's convenient for some kratom supporters to claim otherwise, but I am also a kratom supporter and believe this kind of obvious misinformation harms, rather than furthers the cause.
- GordonS 7y agoI can't edit my post, but to be clear, kratom itself obviously isn't an opioid, but it contains opioid alkaloids.
- loeg 7y agoYep. But the same is more or less true of many pharmaceutical opioid preparations — they may contain paracetamol, binder, or filler in addition to the active opioid compound (e.g., Vicodin). I think it's fair to call the broad category "opioids."
- taxidump 7y agoI was mistaken and had opioid lumped in with opiate.
- heavyset_go 7y agoAlkaloids in kratom bind to mu-opioid receptors, build tolerance, and cessation after chronic use will induce withdrawals.