4 ms·

Depression has plenty of evidence linking it to inflammation That would be interesting. What makes you think so? Any studies you can link to?

lazerpants 7y ago
Somewhat dated now, but this is a good review from 2006. Cytokines sing the blues: inflammation and the pathogenesis of depression https://www.sciencedirect.com/science/article/pii/S1471490605002887 https://www.sciencedirect.com/science/article/pii/S147149060...
- Freegile 7y ago
  Hmm.. that seems like a journalistic article that one would have to pay $41.95 for to read it? I would be more interested in a study. With clearly outlined methology.
  - Analog24 7y ago
    It's a medical journal, Trends in Immunology, the same type of journal that all medical studies are published in. Unfortunately we still have a broken publishing system in the US so it is insanely expensive to read articles/studies published in these journals unless you work somewhere with an institution-level account.
notabee 7y ago
Here's a few for depression and air pollution[1][2] Here's some studies on anti-inflammatory treatments for treatment resistant depression[3] And more relevant to the original topic, 5HT-2A receptor agonists may have anti-inflammatory effects. There's huge potential in a broad class of molecules that have been banned for moral, not medicinal, reasons.[4] Edit: picked another one [5] 1. https://www.ncbi.nlm.nih.gov/pubmed/30719959 https://www.ncbi.nlm.nih.gov/pubmed/30719959 2. https://www.sciencemag.org/news/2017/01/brain-pollution-evidence-builds-dirty-air-causes-alzheimer-s-dementia https://www.sciencemag.org/news/2017/01/brain-pollution-evid... 3.https://www.healio.com/psychiatry/depression/news/online/%7B892f625f-13e6-4a1d-92e5-250ad1be05a2%7D/clinicians-guide-to-anti-inflammatory-treatments-for-major-depression https://www.healio.com/psychiatry/depression/news/online/%7B... 4.https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.503.12 https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supp... 5.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788795/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788795/ That's just some quick googling. There's tons more out there to read!
- Freegile 7y ago
  Sorry, but none of these are studies about the relationship between depression and inflammation treatment. Such a study would have to provide a measurement of the severity of the depression. Then split the patients in two groups. Give one group a placebo and the other one the inflammation treatment. And then compare the depression severity in those groups after the treatment.

lazerpants 7y ago

Somewhat dated now, but this is a good review from 2006. Cytokines sing the blues: inflammation and the pathogenesis of depression https://www.sciencedirect.com/science/article/pii/S1471490605002887 https://www.sciencedirect.com/science/article/pii/S147149060...

Freegile 7y ago
Hmm.. that seems like a journalistic article that one would have to pay $41.95 for to read it? I would be more interested in a study. With clearly outlined methology.
- Analog24 7y ago
  It's a medical journal, Trends in Immunology, the same type of journal that all medical studies are published in. Unfortunately we still have a broken publishing system in the US so it is insanely expensive to read articles/studies published in these journals unless you work somewhere with an institution-level account.

notabee 7y ago

Here's a few for depression and air pollution[1][2] Here's some studies on anti-inflammatory treatments for treatment resistant depression[3] And more relevant to the original topic, 5HT-2A receptor agonists may have anti-inflammatory effects. There's huge potential in a broad class of molecules that have been banned for moral, not medicinal, reasons.[4] Edit: picked another one [5] 1. https://www.ncbi.nlm.nih.gov/pubmed/30719959 https://www.ncbi.nlm.nih.gov/pubmed/30719959 2. https://www.sciencemag.org/news/2017/01/brain-pollution-evidence-builds-dirty-air-causes-alzheimer-s-dementia https://www.sciencemag.org/news/2017/01/brain-pollution-evid... 3.https://www.healio.com/psychiatry/depression/news/online/%7B892f625f-13e6-4a1d-92e5-250ad1be05a2%7D/clinicians-guide-to-anti-inflammatory-treatments-for-major-depression https://www.healio.com/psychiatry/depression/news/online/%7B... 4.https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.503.12 https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supp... 5.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788795/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788795/ That's just some quick googling. There's tons more out there to read!

Freegile 7y ago
Sorry, but none of these are studies about the relationship between depression and inflammation treatment. Such a study would have to provide a measurement of the severity of the depression. Then split the patients in two groups. Give one group a placebo and the other one the inflammation treatment. And then compare the depression severity in those groups after the treatment.