4 ms·
In about 10 years, it will be possible to run a cell lysate sample through a mass spec machine and get what a present-day scientist would call a pretty good pic
by maxander 7y ago
In about 10 years, it will be possible to run a cell lysate sample through a mass spec machine and get what a present-day scientist would call a pretty good picture of everything going on at the proteomic/metabolomic level, in perhaps ~5 hours.
But in that time we will have probably discovered several currently-unappreciated, biologically relevant biochemical mechanisms which we can’t efficiently probe like this. And also it will be considered next to useless because it doesn’t work on single-cell samples. :)
- mnemonicsloth 7y agoI'm trying to change careers into this space. Can you tell me more? (Links appreciated)
- mncharity 7y agoYears ago, I was at a biology outreach-to-the-humanities seminar. Someone asked about the driver of these decades of progress. They were seemingly fishing for some Kuhnian escape from old oppressively restraining dogmas. And were visibly unhappy with the answer that it was mostly economics. Rapidly advancing technology changing the set of questions we can afford to pursue.
- dhash 7y agoCurrently doing this for metabolite analysis. Takt time is at 6 hours, not a long way to go :)