3 ms·
I was impressed how many gene therapy approaches were combined. To target the cancer: - T cell cancer targeting via virus - T cell activation via virus - T
by heisenbit 7y ago
I was impressed how many gene therapy approaches were combined.
To target the cancer:
- T cell cancer targeting via virus
- T cell activation via virus
- T cell outside body multiplication
To deal with symptoms:
- Interleukin-6 surpression (I suspect grown in Chinese Hamster Ovary cells which are the gene tech workhorses)
- vo2maxer 7y agoA good review of Chimeric Antigen Receptor Therapy [1] and its potential modification for solid tumors [2]. Unfortunately both are behind paywall. [1] https://www.nejm.org/doi/full/10.1056/NEJMra1706169 https://www.nejm.org/doi/full/10.1056/NEJMra1706169 [2] https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30426-X https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)3042...
- AllegedAlec 7y ago> - T cell outside body multiplication This is scary though. They tried this before with children with SCID and accidentally gave them cancer [0]. 0: https://scidstuff.wordpress.com/2007/12/18/gene-therapy-cancer-case/ https://scidstuff.wordpress.com/2007/12/18/gene-therapy-canc...