In addition to rapid tolerance buildup (which in a dopaminergic drug would be a danger of rapid progression to overdose), in my experience psilocybin and other

In addition to rapid tolerance buildup (which in a dopaminergic drug would be a danger of rapid progression to overdose), in my experience psilocybin and other psychedelic tryptamines have an inherent moderating effect in many people. I don't really feel like having psychedelic experiences often; it's just not a useful state of being most of the time, and it's not so neurochemically rewarding and physically comfortable that it's highly likely for addiction to develop. It's far less likely to become addicted to psilocybin than THC, alcohol, or caffeine. I do agree that always combining meditation with any substance could lead to a dependence on that substance to experience the deepest meditative states. However, used once in a while (which is the most I really want psychedelics anyway), I can agree with the findings in this paper, the experience sticks with you and can be remembered. pazimzadeh's analogy is spot on. > Right. If you're trying to metaphorically reach the peak of a mountain, psychedelics are like a helicopter that lets you fly around, find the path and even reach the top. > It's possible that you'll grow to rely on the helicopter to climb the mountain, but hopefully what you take away from it is that there is in fact a path (or accept that there's not - and you might has well climb a different mountain).