Yes, you can't change the genome in all the cells of a body. Whether this is necessary or not depends on the disease. For example, for certain conditions, it wo

Yes, you can't change the genome in all the cells of a body. Whether this is necessary or not depends on the disease. For example, for certain conditions, it would be enough to edit some bone marrow stem cells, then put them back into the patient, perhaps at the same time as getting rid of most of their existing bone marrow with chemotherapy or radiotherapy. Another example is editing a specific organ only, such as the retina or the liver.