2 ms·
So this isn’t apoe2? It’s some novel mutation of apoe3?
by mrfusion 7y ago
So this isn’t apoe2? It’s some novel mutation of apoe3?
- gzer0 7y agoCorrect. The APOE3ch alteration falls within a region of the APOE3 protein. Specifically, the article talks about APOE3 R136S or 'Christchurch' (APOE3ch) mutation. A more indepth analysis of the patient's mutation and mechanism(s) of action: https://www.genomeweb.com/sequencing/early-onset-alzheimers-mutation-may-be-mitigated-apoe-variant https://www.genomeweb.com/sequencing/early-onset-alzheimers-...