3 ms·
"off-target" effects on other strains too Source, please? That seems really unlikely given that these are genetic vectors and do not rely on stimulating the im
by masonic 7y ago
"off-target" effects on other strains too
Source, please? That seems really unlikely given that these are genetic vectors and do not rely on stimulating the immune system (which also means fewer side effects).
- mattkrause 7y agoWild, right? I'll try to dig up the ref when I have a moment. The WHO report, linked above, mentions that the bivalent vaccines also have limited effects on other strains, but they're mostly covered by the newer 4/9-valent ones. I'm pretty certain I saw another report suggesting it can hit other strains too, though again, not very effectively. This was the rationale for some of the ancedotes about people's warts disappearing and all that.
- mattkrause 7y agoAlso, I think there's some confusion about how the vaccines work. They're definitely intended to provoke an immune response, but the new ones don't use virus products. Instead, they contain particles (made by yeast) that assemble themselves into something that closely resembles the virus's structure. The immune system raises antibodies against that, priming it for dealing with future infections. More here (including a picture of the virus, which is quite pretty): https://www.ncbi.nlm.nih.gov/pubmed/23800545 https://www.ncbi.nlm.nih.gov/pubmed/23800545