5 ms·

Anti-inflammatory drugs like ibuprofen and aspirin can battle major depression

25 points by spking 7y ago

eurasiantiger 7y ago
Ibuprofen shrinks testicles in regular twice-daily use. https://www.ncbi.nlm.nih.gov/m/pubmed/29311296/ https://www.ncbi.nlm.nih.gov/m/pubmed/29311296/
- armatav 7y ago
  This threads title and this immediate post is quite the emotional roller coaster
- pygy_ 7y ago
  Testicular size isn’t mentioned in that paper, only compensated hypogonadism, i.e. normal testosterone levels maintained through a higher drive from the pituitary gland. The paper also mentions a link between acetaminophen (not ibuprofen) and longer time to pregnancy. Chronic use of NSAID among which ibuprofen can ruin your stomach, and/or your cartilage. Regardless, we are slowly getting out of the dark ages of psychiatry, whose models were until recently as worthy as humor or miasma theory. That’s great.
jacques_chester 7y ago
Yahoo/Verizon throws up a relatively user-hostile blocker asking for full location access. The least obnoxious version I found with a quick search was from The Independent: https://www.independent.co.uk/news/health/depression-painkillers-ibuprofen-statins-fish-oils-study-university-science-technology-wuhan-china-a9175311.html https://www.independent.co.uk/news/health/depression-painkil... And the study itself: https://jnnp.bmj.com/content/early/2019/08/29/jnnp-2019-320912 https://jnnp.bmj.com/content/early/2019/08/29/jnnp-2019-3209...
- LorenPechtel 7y ago
  Jokes on them--my "location" is on the wrong continent.
proverbialbunny 7y ago
There are multiple kinds of depression, and because of that there is never going to be a one pill cure all, until we start studying different kinds of depression. However with that being said, there is a correlation between some depression and stomach inflammation. For many emotional feelings are tied to the stomach. Something as small as a stomach ache can sometimes leave a person in a cruddy mood. I wonder if this is why anti-inflammatories help. (On a more cheerful note, anti-inflammatories got spell checked to anti-flamethrowers on my computer.)

25 points by spking 7y ago

Ibuprofen shrinks testicles in regular twice-daily use. https://www.ncbi.nlm.nih.gov/m/pubmed/29311296/ https://www.ncbi.nlm.nih.gov/m/pubmed/29311296/

armatav 7y ago
This threads title and this immediate post is quite the emotional roller coaster
pygy_ 7y ago
Testicular size isn’t mentioned in that paper, only compensated hypogonadism, i.e. normal testosterone levels maintained through a higher drive from the pituitary gland. The paper also mentions a link between acetaminophen (not ibuprofen) and longer time to pregnancy. Chronic use of NSAID among which ibuprofen can ruin your stomach, and/or your cartilage. Regardless, we are slowly getting out of the dark ages of psychiatry, whose models were until recently as worthy as humor or miasma theory. That’s great.

jacques_chester 7y ago

Yahoo/Verizon throws up a relatively user-hostile blocker asking for full location access. The least obnoxious version I found with a quick search was from The Independent: https://www.independent.co.uk/news/health/depression-painkillers-ibuprofen-statins-fish-oils-study-university-science-technology-wuhan-china-a9175311.html https://www.independent.co.uk/news/health/depression-painkil... And the study itself: https://jnnp.bmj.com/content/early/2019/08/29/jnnp-2019-320912 https://jnnp.bmj.com/content/early/2019/08/29/jnnp-2019-3209...

LorenPechtel 7y ago
Jokes on them--my "location" is on the wrong continent.

proverbialbunny 7y ago

There are multiple kinds of depression, and because of that there is never going to be a one pill cure all, until we start studying different kinds of depression. However with that being said, there is a correlation between some depression and stomach inflammation. For many emotional feelings are tied to the stomach. Something as small as a stomach ache can sometimes leave a person in a cruddy mood. I wonder if this is why anti-inflammatories help. (On a more cheerful note, anti-inflammatories got spell checked to anti-flamethrowers on my computer.)