3 ms·
Fentanyl is more like 100x the potency of morphine. And while it's true that morphine is the strongest opiate directly present in opium, codeine is converted in
by darawk 7y ago
Fentanyl is more like 100x the potency of morphine. And while it's true that morphine is the strongest opiate directly present in opium, codeine is converted into morphine by cytochrome P450 in the liver, increasing the effective morphine dose. Here's some citations:
https://www.oregonpainguidance.org/wp-content/uploads/2018/02/Powers_et_al-2017-Journal_of_Forensic_Sciences.pdf?x91687 https://www.oregonpainguidance.org/wp-content/uploads/2018/0...