4 ms·
> Here, we show that male, but not female, offspring of Δ9-tetrahydrocannabinol (THC)-exposed dams, a rat PCE model, exhibit extensive molecular and synaptic ch
by jMyles 7y ago
> Here, we show that male, but not female, offspring of Δ9-tetrahydrocannabinol (THC)-exposed dams, a rat PCE model, exhibit extensive molecular and synaptic changes in dopaminergic neurons of the ventral tegmental area, including altered excitatory-to-inhibitory balance and switched polarity of long-term synaptic plasticity.
Very possible that this effect will not be observed in humans. Certainly not a good reason to cease cannabis use if it's part of your pregnancy or birth plan, coordinated with experienced prenatal and neonatal professionals.
The opening of the abstract costs this study substantial credibility in my opinion:
> The increased legal availability of cannabis has led to a common misconception that it is a safe natural remedy for, among others, pregnancy-related ailments such as morning sickness.
There is no source provided for the claim that increased legal availability has led to a change in perception, but the use of this phrase to open the abstract betrays an unambiguous agenda.
I'll wait until more human longitudinal studies (the current corpus of which includes many which appear favorable to cannabis as part of a prenatal regimen) before changing my mind.