Can anyone recommend a good font which has good differentiation between lowercase letters and uppercase letters (when dealing with both lower/upper unicode subs

Can anyone recommend a good font which has good differentiation between lowercase letters and uppercase letters (when dealing with both lower/upper unicode subscripts and superscripts) Presumably lowercase letters would have a rounder o, and uppercase a flatter/blockier O, i.e. all lower/upper have some differentiation, and no lowercase character where it is just a scaled down version of the upper. would be eternally grateful.