Ok that's an animal study that suggests some changes in microbiome, still need to show its applicable to humans and that the changes are meaningful to health in

Ok that's an animal study that suggests some changes in microbiome, still need to show its applicable to humans and that the changes are meaningful to health in anyway. The second paper doesn't make any definitive claims on health or humans either. There are reviews of multiple blinded, randomized controlled trials showing no adverse health outcomes. Are any such meta-analyses that show there are? Animal trials at extremely and dosages coupled with some human trials suggesting (without controlling for confounding factors) possible changes in gut microbiome without demonstrating any meaningful health outcomes is significantly less convincing.