Ventilation/offgassing is a fairly minor concern, especially for small projects where you don't get much heat release from the reaction, and you are not baking

Ventilation/offgassing is a fairly minor concern, especially for small projects where you don't get much heat release from the reaction, and you are not baking it. Your kitchen extractor fan is probably enough. You can try it out with a small test, say total amount of epoxy equal to 2 tablespoons, and see how that goes. I would actually expect more of a ventilation requirement from your 3D printer! Here is one set of safety recommendations for working with ABS/PLA: https://www.safety.rochester.edu/ih/3Dprinters.html https://www.safety.rochester.edu/ih/3Dprinters.html But if you are really worried, go get a 3M 7502 mask with a 6001 organic vapor cartridge. These are cheap. That's what the manufacturer (West System) MSDS says to use in case of no ventilation. Skin contact is a bigger concern. 1 in 5 develop dermatitis upon skin contact, and some get more severe allergic reactions. So wear good gloves, blue nitrile ones that fit well with decent thickness, not the cheap latex stuff.