Well, with the GDUFA each genetic manufacturer has to pay the same large inspection fee regardless of how much a drug they produce and they have to pay it far a

Well, with the GDUFA each genetic manufacturer has to pay the same large inspection fee regardless of how much a drug they produce and they have to pay it far ahead of the time they start selling the drug. This has driven a dramatic consolidation that's resulted in things like the recent bospirone shortage in addition to the recent sudden spike in generic prices.