Yes, and there's a good chance those who do make the trip will not be "natural" humans (as hibernation, zero-g adaptations, or increased lifespan would be inval

Yes, and there's a good chance those who do make the trip will not be "natural" humans (as hibernation, zero-g adaptations, or increased lifespan would be invaluable in sub-light interstellar trips) or even biological, so… Let's just say people.