One interesting tidbit that this article doesn’t mention is that fiber orientation of cartilage is fundamental to the functionality of different cartilaginous t

One interesting tidbit that this article doesn’t mention is that fiber orientation of cartilage is fundamental to the functionality of different cartilaginous tissues. It’s similar to how fiber orientation in carbon fiber parts will be adjusted to provide strength and durability in specific directions. Articular cartilages likely is somewhat more evenly oriented, but tendons are highly aligned to length and meniscus aligned in a hoop like direction. New or repaired cartilage in different tissues need exercise and other forms of mechanical agitation to align properly. Even if we could repair all cartilage readily we’d still need lots of physical therapy and to regrow damaged tissue at a slow pace. So no miracle sir on the couch cures even if this works. On another the meniscus (and vertebrae discs?) loose blood flow after mid-30 or thereabouts and might make effective delivery or healing more difficult. It’ll be interesting to see what happens in the next decade or two!