Good info, but bad formatting. Same quote, more mobile friendly: - He just possibly infected his whole digestive system. Not just small intestine, but stomach

Good info, but bad formatting. Same quote, more mobile friendly: - He just possibly infected his whole digestive system. Not just small intestine, but stomach as well. Furthermore, AAV can potentially exhibit transcytosis through epithelial layers, suggesting that it's possible the virus infected more than just his digestive system. - He did not determine an appropriate dose, and so he likely infected with a HUGE genetic payload. Overexpression with AAV can kill infected cells, which means this man is risking his digestive lining. - Neither the promoter nor the encoded protein itself are human, potentially risking (possibly severe) autoimmune reaction. - There are few/no long-term studies on effects of AAV integration and expression in humans. There is indeed evidence that AAV increases risk of cancer, almost certainly in a dose- dependent manner. - AAVs could integrate randomly into your genome in low frequencies (0.1% to 1%), meaning that they could just by chance disrupt a gene you really need to not get cancer.