Mutations in nature also aren't random and generally small. Different types occur with different probability, and nucleotides are replaced with other nucleotide

Mutations in nature also aren't random and generally small. Different types occur with different probability, and nucleotides are replaced with other nucleotides and not some new life form. But just like startups, mutations are blind to whether they will be beneficial or not. Lamarck's idea of inheritance is not really related to this.