I think this has the memory on board the CPU card, so it shouldn't affect anything there. What i'd be worried about is the total number of pci-e lanes exposed

I think this has the memory on board the CPU card, so it shouldn't affect anything there. What i'd be worried about is the total number of pci-e lanes exposed by the slot for the cpu, that'll bottleneck most systems these days thanks to nvme storage and other peripherals.