Well, they did took over when it came to desktop. But in the 2000s the web became popular as a target for applications so their desktop dominance wasn't the onl

Well, they did took over when it came to desktop. But in the 2000s the web became popular as a target for applications so their desktop dominance wasn't the only thing that mattered. However in their niches MS Access and Excel (VB not anymore but that was because Microsoft forcefully killed it, not because the developers that used it decided by themselves to move away from it) are still dominant (in fact so dominant that they overflow from these "niches" - see how many stories of Excel VBA doing things that weren't "supposed" to be done in Excel).