3 ms·

Caffeine is on the list. So a breakfast of coffee and grapefruit is a medically proven stimulating start to the day?

• throwaway8941 7y ago
  Sadly, no. >One study, by Maish and colleagues in Pharmacotherapy 1996, looked at whether grapefruit juice increased caffeine effects and found little or no difference in blood concentrations and blood pressure when caffeine was given with and without GFJ. Other research has confirmed these results. Since specific enzyme systems most often metabolize similar chemicals, one would not necessarily expect GFJ to affect other stimulants, but this is far from conclusive. https://erowid.org/ask/ask.php?ID=2726 https://erowid.org/ask/ask.php?ID=2726
  • foobarian 7y ago
    IIRC naringin has an indirect effect on coffee, where it inhibits an enzyme that is involved in metabolizing caffeine. So the outcome is that the effect of your coffee lasts a lot longer, instead of being more potent. Edit: Now that I go looking again, there is also evidence against this conclusion: https://www.eurekalert.org/pub_releases/2003-04/aps-rsm040903.php https://www.eurekalert.org/pub_releases/2003-04/aps-rsm04090...
• ghettoimp 7y ago
  It would certainly be a horrific jolt to your taste buds... geish.